Vigabatrin and tiagabine might have antipanic properties.
نویسندگان
چکیده
منابع مشابه
A controlled study comparing visual function in patients treated with vigabatrin and tiagabine.
OBJECTIVE Vigabatrin treatment is frequently associated with irreversible retinal injury and produces retinal electrophysiological changes in nearly all patients. Concern has been raised that tiagabine and other antiepilepsy drugs (AEDs) that increase brain gamma-aminobutyric acid (GABA) might produce similar electrophysiological and clinical changes in visual function. The study compared visua...
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Tiagabine (TGB) and vigabatrin (VGB) are two novel anticonvulsant compounds reported to exert their pharmacological effects via an action on the gamma-aminobutyric acid (GABA) system. We have investigated the effects of acute exposure of these drugs on the uptake of GABA into rat cortical astrocytes in primary culture. Astrocytes were prepared from the cerebral cortices of one day-old rat pups ...
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عنوان ژورنال:
- Journal of psychopharmacology
دوره 18 3 شماره
صفحات -
تاریخ انتشار 2004